Ziconotide

N-type calcium channel blocker for severe chronic pain. Conopeptide-derived analgesic from cone snail venom, providing potent spinal cord-mediated pain relief without opioid tolerance.

Get a free quote

Description
Additional information

Ziconotide is a synthetic 25-amino acid polybasic peptide and the first-in-class non-opioid analgesic derived from the venom of the marine cone snail Conus magus (omega-conotoxin MVIIA). It selectively blocks N-type voltage-gated calcium channels (Cav2.2) in the spinal cord, providing potent pain relief without the risk of opioid-related side effects or addiction.

Parameter	Specification
CAS	107452-89-1
Molecular Formula	C₁₀₂H₁₇₂N₃₆O₃₂S₇
Molecular Weight	2639.13 g/mol
Category	Oncology/Endocrine
Purity	≥99%
Status	GMP-compliant, FDA-ready
Applications	Severe chronic pain, intrathecal analgesia, opioid alternative, neuropathic pain