Eptifibatide

GPIIb/IIIa antagonist for acute coronary syndrome. Cyclic heptapeptide inhibiting platelet aggregation, reducing ischemic complications in ACS and PCI procedures.

Eptifibatide, marketed under the brand name Integrilin, is a cyclic heptapeptide and the first FDA-approved platelet glycoprotein IIb/IIIa (GPIIb/IIIa) receptor antagonist derived from a natural source. Originally isolated from the venom of the pygmy rattlesnake (Sistrurus miliarius barbouri), eptifibatide was structurally optimized to become a potent, selective, and rapidly reversible inhibitor of platelet aggregation. It received FDA approval in 1998 and has since become a cornerstone therapy in interventional cardiology.

Parameter Specification
CAS 188627-80-7
Molecular Formula C₃₅H₄₉N₁₁O₉S₂
Molecular Weight 831.96 g/mol
Category Cardiovascular
Purity ≥99%
Status GMP-compliant, FDA-ready
Applications Acute coronary syndrome, PCI, platelet aggregation inhibition

 

CAS

188627-80-7

Applications

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