Vapreotide
Somatostatin analog for esophageal varices and GI bleeding. Potent vasoconstrictive and antisecretory properties for acute hemorrhage control in portal hypertension.
Vapreotide (also known as RC-160 or BMY-41606) is a synthetic cyclic octapeptide analogue of somatostatin, a naturally occurring peptide hormone that inhibits the secretion of growth hormone and various other hormones. Structurally engineered with two D-amino acids (D-Phe at position 1 and D-Trp at position 4) and a Cys2-Cys7 disulfide bridge, vapreotide exhibits significantly enhanced metabolic stability and receptor selectivity compared to native somatostatin.
| Parameter | Specification |
| CAS | 103222-11-3 |
| Molecular Formula | C₅₇H₇₀N₁₂O₉S₂ |
| Molecular Weight | 1131.37 g/mol |
| Category | Oncology/Endocrine |
| Purity | ≥99% |
| Status | GMP-compliant, FDA-ready |
| Applications | Esophageal varices, GI bleeding, portal hypertension, pancreatitis |
| CAS | 103222-11-3 |
|---|---|
| Applications | Esophageal Variceal Bleeding, GI Bleeding, Somatostatin Analog |
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